Microbiologist · Scientist · Developer

Mark
Zhang

At the intersection of microbiology, biopharmaceuticals, and software engineering. From stomach cancer research to HPLC analytics to digital pathology — bridging the bench and the terminal.

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// professional experience

Where I've worked.

Stomach Cancer Research Lab

Microbiology Researcher

Investigated the role of H. pylori and the gastric microbiome in stomach cancer pathogenesis. Performed bacterial culture, DNA extraction, PCR amplification, and microbiome sequencing analysis to characterise tumour-associated microbial communities.

Cell Culture PCR 16S rRNA Aseptic Technique H. pylori
0 25 50 75 100 Retention Time (min) mAU 3.2 min 7.8 min
PPD (now Thermo Fisher Scientific)

Biopharmaceutical Analyst

Performed bioanalytical testing on drug candidates using HPLC and LC-MS/MS methods under GLP-compliant conditions. Executed method validation, sample preparation, and data analysis in support of pre-clinical and clinical pharmacokinetic studies.

HPLC LC-MS/MS GLP Method Validation Empower
H&E
Tempus AI

Histology Technician

Processed clinical tissue specimens for molecular and pathology workflows supporting precision medicine. Performed sectioning, H&E staining, immunohistochemistry, and quality review of slides destined for genomic sequencing and AI-driven diagnostics.

Microtomy H&E Staining IHC FFPE Processing Digital Path

Bench science meets
software.

I'm a scientist and developer with hands-on experience across microbiology, bioanalytical chemistry, and histopathology — combined with a genuine passion for building software that makes laboratory and research workflows more efficient.

My career has taken me from characterising the gastric microbiome in stomach cancer specimens, to running GLP-compliant HPLC assays on drug candidates at PPD (now Thermo Fisher), to preparing and reviewing clinical tissue samples for AI-driven diagnostics at Tempus.

When I'm not at the bench or the keyboard, I'm exploring the intersection of life-science data and code — building tools, automating pipelines, and looking for the next interesting problem to solve.

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Industry positions
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Samples processed
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Lab disciplines
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Programming languages

// skills & tools

What I work with.

🧬 Microbiology

  • Bacterial Culture95%
  • PCR / qPCR88%
  • Microbiome Analysis80%
  • Aseptic Technique95%
  • BSL-2
  • Gram Stain
  • 16S rRNA
  • DNA Extraction

⚗️ Bioanalytical

  • HPLC92%
  • LC-MS/MS78%
  • Method Validation85%
  • GLP Compliance90%
  • Empower
  • Waters
  • Sample Prep
  • PK Studies

🔬 Histology & Code

  • H&E / IHC Staining90%
  • Microtomy88%
  • Python / Node.js82%
  • Web Development75%
  • FFPE
  • Digital Path
  • Python
  • JavaScript
  • AWS

// projects

Selected work.

Microbiology

Gastric Microbiome Study

Characterized microbial community composition in stomach cancer biopsy specimens using 16S rRNA sequencing and bioinformatics analysis to identify potential pathogenic signatures.

Biopharma

HPLC Method Development

Developed and validated HPLC methods for quantifying drug metabolites in biological matrices under GLP conditions, supporting clinical pharmacokinetic data submissions.

Histology

Clinical Tissue QC Pipeline

Contributed to tissue processing and quality review workflows at Tempus, ensuring slide quality met thresholds for downstream genomic sequencing and AI-based pathology analysis.

Software

Movie Bot

Discord bot built with Node.js and discord.js that searches the TMDB API and returns interactive poster collage embeds with button-based navigation.

Research

H. pylori Virulence Profiling

Profiled CagA and VacA genotypes across clinical H. pylori isolates to correlate virulence factor expression with disease severity and tissue pathology findings.

Analytical

Bioanalytical Data Automation

Built Python scripts to automate sample tracking, data reformatting, and report generation from Empower chromatography outputs, reducing manual processing time.

Let's connect.

Open to laboratory scientist roles, research collaborations, and opportunities where bench science meets software. Drop me a message — I try to respond within 48 hours.